Unit 3 Concept Maps
An Overview of Microbial Pathogenesis
Factors That Promote Bacterial Colonization: Introduction
- The Ability to Use Motility or Other Means to Contact Host Cells and Disseminate Within a Host
- The Ability to Adhere to Host Cells and Resist Physical Removal
- The Ability to Invade Host Cells
- The Ability to Compete for Nutrients such as Iron
- Overview of Phagocytosis and the Complement Pathways
- The Ability to Resist Innate Immunity: Resisting Phagocytic Engulfment and Antibacterial Peptides
- The Ability to Resist Innate Immunity: Resisting Phagocytic Destruction
- The Ability to Resist Adaptive Immunity
Virulence Factors that Damage the Host
- Synthesize and Secrete Inflammatory Cytokines and Chemokines in Response to PAMPs
- Systemic Inflammatory Response Syndrome (SIRS)
- The Ability to Produce Harmful Exotoxins
- Type I Toxins (Superantigens)
- Type II Toxins (Toxins that Damage Host Cell Membranes)
- Type III Toxins (Toxins that Interfere with Host Cell Functions)
- The Ability to Induce Autoimmune Responses